Dr. Elena Alberdi

Dr. Alberdi completed her PhD in the Department of Biochemistry and Molecular Biology at the University of Navarra in Spain. She received a Postdoctoral Research Award on her studies about the molecular characterization of the neurotrophic factor PEDF. Recently, her research focus shifted to Alzheimer’s diseases, where her main research goal is to identify mechanisms of signalling and damage in amyloid oligomers on neurons and glia with the intention to finding new biomarkers and new treatments against AD.

Research interests:

• Oligodendrocyte proliferation and dynamics
• Myelin remodelling
• Alzheimer’s disease

Selected publications: 

• Asier Ruiz, Jone Zuazo, Carolina Ortiz-Sanz, Celia Luchena, Carlos Matute, Elena Alberdi, Sephin1 protects neurons against excitotoxicity independently of the integrated stress response, 2021, International Journal of Molecular Science, doi: 10.3390/ijms21176088

• Ortiz-Sanz C, Gaminde-Blasco A, Valero J, Bakota L, Brandt R, Zugaza JL, Matute C, Alberdi E, Early effects of amyloid β oligomers on dendritic spine dynamics and arborization in hippocampal neurons, Frontiers in Synaptic Neuroscience, doi: 10.3389/fn-syn.2020.00002

• Diaz-Aparicio I, Paris I, Sierra-Torre V, Plaza-Zabala A, Rodr.guez-Iglesias N, M.rquez-Ropero M, Beccari S, Huguet P, Abiega O, Alberdi E, Matute C, Bernales I, Schulz A, Otrokocsi L, Sperlagh B, Happonen KE, Lemke G, Maletic-Savatic M, Valero J, Sierra A Microglia actively remodel adult hippocampal neurogenesis through the phagocytosis secretome, Journal of Neuroscience, doi: 10.1523/JNEUROSCI.0993-19.2019